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Search Results for " Hep G2 "

ターゲット

Estrogen Receptor/ERR Estrogen/progestogen Receptor

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T1579	Mestranol	Devocin,Norquen,Menophase	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Mestranol (Devocin), a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T62905	GLS-1-IN-1
	GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
T30111	AR 12465	AR-12465
	AR 12465 is a trapidil derivative which may affect LDL receptor mediated uptake and degradation of 125 I-LDL by human skin fibroblasts (HSF) and human hepatic cells (HEP G2).
T71610	Docosylferulate
	Docosylferulate is a biochemical that has been studied for its inhibition on Hep G2 cells and anti-tumor activities.
T73422	CPT-Se4		Topoisomerase
	CPT-Se4, a seleno-derivative of Camptothecin (CPT), exhibits enhanced efficacy in cancer cell eradication and tumor suppression. It reduces the GSH/GSSG balance and total thiol content while increasing ROS concentrations...		Topoisomerase
T78068	O-allylvanillin		Others
	O-Allylvanillin, an O-allylchalcone derivative, exhibits anti-cancer properties by inhibiting the growth of THP-1, HL60, Hep-G2, and MCF-7 cells with IC50 values of 74.76 μM, 63.52 μM, 90.99 μM, and 90.11 μM, respectivel...		Others
T63304	Topoisomerase II inhibitor 9
	Topoisomerase II inhibitor 9 is a Topo II inhibitor (IC50: 0.97 μM) and DNA embedding agent (IC50: 43.51 μM) that blocks the Hep G-2 cell cycle in the G2/M phase and induces apoptosis.
T73421	CPT-Se3		Topoisomerase
	CPT-Se3, a camptothecin (CPT) seleno-derivative, exhibits enhanced anticancer efficacy by effectively killing cancer cells and hindering tumor proliferation. This compound diminishes the GSH/GSSG ratio and total thiols w...		Topoisomerase
T76527	Hepatitis B Virus Receptor Binding Fragment
	Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980), a synthetic peptide analog, specifically binds to Hep G2 cells and is a potential immunogen anticipated to induce protective antibodies through the ...
T82493	EGFR/HER2/DHFR-IN-2		EGFR
	EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively. It exhibits anticancer activity, displaying IC50 values of 9.14, 7.33, 14.1...		EGFR
T79915	Antioxidant agent-15		COX
	Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM. Furthermore, it effectively inhibits tumor cell growth in Hela, Hep G2, and Caco-2 cells, with ...		COX
T62405	KDM1/CDK1-IN-1
	KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 μM) and CDK1 (IC50: 0.078 μM). kDM1/CDK1-IN-1 blocks the cell cycle of HOP-92 cells in G2/M phase and induces apoptosis. KDM1/CDK1-IN-1 is highly cyt...
T78855	Anticancer agent 157		NO Synthase
	Anticancer Agent 157 (compound 15) is a nitric oxide (NO) inhibitor with IC50 values of 0.62 μg/mL, exhibiting both anti-inflammatory and anticancer effects. It interacts with inducible NO synthase (iNOS) and caspase 8, ...		NO Synthase
T78588	Cochliodone A
	Cochliodone A, a bioactive compound isolated from the deep-sea fungus Chaetomium sp., exhibits both antibacterial and anticancer properties. This substance demonstrates toxicity against multiple bacterial strains, as evi...

Compounds

Mestranol

T1579

Synonym: Devocin,Norquen,Menophase

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Target: Topoisomerase

Topoisomerase II inhibitor 9

Target: Topoisomerase

Hepatitis B Virus Receptor Binding Fragment

カタログ番号	製品名	別名	ターゲット
T5654	Musk ketone		Others
	Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.		Others
TN2225	Soyasapogenol B		Apoptosis , Autophagy
	Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.		Apoptosis , Autophagy
TN4562	Oleoside 11-methyl ester	Methyloleoside	Others
	Oleoside 11-methyl ester (Methyloleoside) is a natural product.		Others
T13897	Soyasaponin III		Others
	Soyasaponin III is one of the main potentially bioactive saponins found in soy (Glycine max) and related products,and can induce apoptosis in Hep-G2 cells.		Others
TN3728	Cudraxanthone L		Others
	Cudraxanthone L shows the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.		Others
TN5941	2,3-O-Isopropylidenyl euscaphic acid	Euscaphic acid acetonide
	2,3-O-Isopropylidenyl euscaphic acid shows good hepatoprotective effect,the EC50 value of 88.36±3.25 uM in Hep G2 cells.
T81365	Protoapigenone
	Protoapigenone, an antineoplastic agent extracted from ferns, demonstrates notable inhibitory activity against various cancer cell lines, including Hep G2, Hep 3B, MCF-7, A549, and MDAMB-231. The respective IC50 values a...
TN4711	Onitin		Others
	Onitin shows super-oxide and DPPH free radical scavenging effects.It also exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.		Others
TN4843	Pterisolic acid A		Others
	Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines.		Others
TN5961	Gardenolic acid B
	Gardenolic acid B shows promising hepatoprotective effects on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells. Gardenolic acid B shows significant effects on terminating early pregnancy in rats.
TN1464	Camellianin A		RAAS
	Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the signif...		RAAS
TN1368	Alisol C		Others
	Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxici...		Others
TN5154	Torilolone		Others
	Torilin and torilolone show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 values are 20.6 +/- 1.86 and 3.6 +/- 0.1 microM, respectively; and silybin as a positive c...		Others
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to in...
TN2190	Scoulerine		Apoptosis , Beta-Secretase , BACE , Parasite
	Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.		Apoptosis , Beta-Secretase , BACE , Parasite

天然物製品

Target: Apoptosis, Autophagy

Oleoside 11-methyl ester

TN4562

Synonym: Methyloleoside

2,3-O-Isopropylidenyl euscaphic acid

TN5941

Synonym: Euscaphic acid acetonide

Cudratricusxanthone A

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03655	GADD45G Protein, Human, Recombinant	Human	E. coli
	GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...

GADD45G Protein, Human, Recombinant

TMPY-03655

Species: Human

Expression System: E. coli